What is Leneva?

Leneva is an allograft adipose matrix derived from donated human tissue. It contains:

• Extracellular matrix proteins
• Collagens
• Growth factors
• Adipose-derived stem cells

Mechanism of Action

When injected into the plantar aspect of the foot, Leneva:

1. Provides immediate cushioning
2. Stimulates adipogenesis (formation of new fat cells)
3. Promotes angiogenesis (formation of new blood vessels)

Encourages tissue regeneration

Indications for Leneva Treatment

• Metatarsalgia due to fat pad atrophy
• Plantar heel pain associated with fat pad deterioration
• Diabetic foot ulcer prevention in high-risk areas
• Pes cavus (high arch) foot type with increased plantar pressures

Benefits of Leneva

1. Long-lasting results: Can provide relief for up to 12 months or more
2. Natural feel: Mimics the properties of native fat tissue
3. Biocompatible: Minimal risk of allergic reactions
4. Promotes tissue regeneration: Stimulates the body’s own healing processes
5. Minimally invasive: Outpatient procedure with quick recovery

Procedure

• Performed under local anesthesia
• Leneva is injected into the subcutaneous tissue of the affected area
• Multiple injection sites may be used for optimal distribution
• The procedure typically takes 15-30 minutes

Post-Procedure Care

• Avoid strenuous activities for 24-48 hours
• Use of supportive footwear or orthotics may be recommended
• Follow-up appointments to monitor progress

Potential Side Effects

While generally well-tolerated, some patients may experience:

• Temporary edema at the injection site
• Mild ecchymosis
• Short-term discomfort